Fingerprinting celiac disease in Portugal towards remission
CeliAct project aims to characterize celiac disease in Portugal, to create a biobank of serum and stool samples from celiac patients and their families and to study the immunogenic portions of gluten to contribute to the future development of a treatment that protects celiac patients from the attack of their immune system when stimulated by gluten. Celiac disease is the only autoimmune disease in which its trigger, gluten (present in wheat, rye, barley and oat) is known. However, only 10% of the genetically susceptible people develop the disease and some of these people even have positive antibodies but remain asymptomatic. Studying their intestinal microbiota is the next step in this exploratory project.
Sónia Gonçalves Pereira
18 months (2019 – 2021)
INSTITUTIONAL AND INDUSTRY PARTNERS
Hospital Center of Leiria, EPE
University of Coimbra