CHRONO-C2C
From Concept to Certification: A Digital Tool for Chrononutrition Interventions
The CHRONO-C2C project is an innovative exploratory initiative designed to assess the role of chrononutrition in managing obesity and its associated comorbidities. The project focuses on optimising a digital application to support interventions based on individual chronotype, while verifying the regulatory requirements needed for its qualification as Software as a Medical Device (SaMD).
The core proposal of CHRONO-C2C is to explore how aligning dietary patterns with the circadian rhythm may impact clinical and metabolic parameters in individuals with obesity. To this end, the study evaluates the feasibility of using a digital platform to record and monitor data on chronotype and eating habits, thereby promoting better adherence to personalised nutritional interventions.
Supported by a multidisciplinary team of experts in nutrition, chronobiology, bioinformatics, and medical device regulation, CHRONO-C2C also engages patient associations to ensure the application meets end-user needs and aligns with best practices in digital health. As an exploratory study, CHRONO-C2C ultimately aims to inform future clinical trials and contribute to the development of technology-based interventions for obesity management.
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Keywords: Chrononutrition, chronotype, medical device, mHealth, regulation
Principal Investigator: Maria Pedro Guarino (maria.guarino@ipleiria.pt)
Research Team:
- ciTechCare: Cátia Pontes (cátia.pontes@ipleiria.pt), Sara Dias (Sara.Dias@ipleiria.pt)
- ULS da Região de Leiria (Unidade Local de Saúde da Região de Leiria): Nuno Vicente
- ISCTE-Sintra: Catarina Reis (Catarina.Reis@iscte-iul.pt)
Duration: 18 months (2026 – 2027)
Institutional Partners and Others
- VOID Software: João Mota
- NERLEI Associação Empresarial da Região de Leiria: Henrique Carvalho
Reference: 2024.17039.PEX, https://doi.org/10.54499/2024.17039.PEX
Funding: FCT – Fundação para a Ciência e Tecnologia